Registration of acute viral hepatitis – an “Iceberg phenomenon”

K. A. Talalayev, E. V. Kozishkurt


The quality of registration of acute liver damage caused by hepatitis A, B and C viruses can be questioned. A comparative study of the frequency of detection of serological markers of acute liver damages associated with three pathogens and indicators of officially registered morbidity was carried out. It has been established that in some cases the diagnosis of hepatitis A is established only on the basis of clinical symptoms and the exclusion of markers of acute damage by other hepatitis viruses. The results of serological studies on the detection of aHBcor IgM in patients with hepatitis symptoms suggest that in half of cases there is an under-registration of acute hepatitis B. The estimated incidence of acute hepatitis C, according to the identified markers (aHCV IgM), is more than 10 times higher than the recorded level. It is necessary to optimize the information subsystem of epidemiological surveillance of this group of diseases by organizing a vertical line between the diagnostic and therapeutic link in the health care system.


acute hepatitis A, B, C; calculated morbidity; serological marker; acute liver damage

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Jacobsen K. The Global Prevalence of Hepatitis A Virus Infection and Susceptibility: A Systematic Review. WHO, Geneva. 2010. P. 21.

Stanaway, J. D., Flaxman, A.D., Naghavi, M., Fitzmaurice, C., Vos, T., Abubakar, I. et al. The global burden of viral hepatitis from 1990 to 2013: findings from the global burden disease study 2013. Lancet. 2016; 388: 1081–1088.

Iqbal, K., Klevens, R. M., Kainer, M. A., Baumgartner, J., Gerard, K., Poissant, T. et al. Epidemiology of acute hepatitis B in the united states from population-based surveillance, 2006–2011. Clin Infect Dis. 2015; 61: 584–592.

Ott, J. J., Horn, J., Krause, G., and Mikolajczyk, R. T. Time trends of chronic HBV infection over prior decades – A global analysis. J Hepatol. 2017; 66: 48–54.

Schweitzer, A., Horn, J., Mikolajczyk, R. T., Krause, G., and Ott, J. J. Estimations of worldwide prevalence of chronic hepatitis B virus infection: A systematic review of data published between 1965 and 2013. Lancet. 2015; 386: 1546–1555.

Chen, C. - L., Yang, J. - Y., Lin, S. - F., Sun, C. - A., Bai, C.-H., You, S.- L. et al. Slow decline of hepatitis B burden in general population: Results from a population-based survey and longitudinal follow-up study in Taiwan. J Hepatol. 2015; 63: 354–363.

Coppola, N., Alessio, L., Gualdieri, L., Pisaturo, M., Sagnelli, C., Caprio, N. et al. Hepatitis B virus, hepatitis C virus and human immunodeficiency virus infection in undocumented migrants and refugees in southern Italy, January 2012 to June 2013. Euro Surveill. 2015; 20: 30009.

Hampel, A., Solbach, P., Cornberg, M., Schmidt, R. E., Behrens, G. M., and Jablonka, A. Current seroprevalence, vaccination and predictive value of liver enzymes for hepatitis B among refugees in Germany. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016; 59: 578–583.

Ansaldi F., Orsi F., Sticchi L., Bruzzone B., Icardi G. Hepatitis C virus in the new era: Perspectives in epidemiology, prevention, diagnostics and predictors of response to therapy. World J Gastroenterol. 2014 Aug 7; 20(29): 9633–9652.

Wise M., Bialek S., Finelli L., Bell B. P, Sorvillo F. Changing trends in hepatitis C-related mortality in the United States, 1995-2004. Hepatology. 2008;47:1128–1135.

Yan Z., Fan K., Wang Y., Fan Y., Tan Z., Deng G. Changing pattern of clinical epidemiology on hepatitis C virus infection in SouthWest China. Hepat Mon. 2012;12:196–204.



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ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

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