Relationship between intestinal microbiota and thyroid homeostasis

Anna Fabian-Danielewska, Monika Stecko, Agata Wawryków, Magdalena Żukowska, Katarzyna Korabiusz


The human digestive tract is inhabited by hundreds of bacterial species, both aerobic and anaerobic, bacteriophages, viruses and fungi that collectively are referred to as intestinal microbiota. Microbiota has a significant impact on the production and maintenance of immunological, hormonal and metabolic homeostasis. Dysbiosis is present in inflammations, e.g. intestinal inflammation, autoimmune diseases, e.g. multiple sclerosis, type 1 diabetes, rheumatic diseases, metabolic disorders such as obesity or type 2 diabetes, and mental illness. Currently, numerous studies are underway on the effect of microbiota on thyroid autoimmune diseases. . It seems, that microbiota has a small, if any, effect on the metabolism of iodine and selenium - elements particularly responsible for thyroid homeostasis. However, the relationship between thyroid function and the gastrointestinal tract has been proven.


microbiota; thyroid

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J. Hardina, A.Banning., A Kipp The gastrointestinal microbiota affects the selenium status and selenoprotein expression in mice. J.Nutr. Biochem. 2009;20:638-648.

C.Virili, M.Centanni: Does microbiota composition affect thyroid homeostasis?. Endocrine. 2015; 49:583-587

F. Zhao, J.Feng, J.Li, L.Zhao I in.: Alterations of the Gut Microbiota in Hashimoto’s Thyroiditis Patients. Thyroid. 2018: 2(28): 175-186

C.Virili, P Fallahi, A.Antonelli, S.Benvenga, M.Centanni: Gut microbiota and Hashimoto’s thyroiditis. Rev Endocr Metab Disord. Publish online: 08 October 2018.

H.Kohling, S.Plummer, J. Marchesi, K.Davidge, M.Ludgate: The microbiota and autoimmunity: Their role in thyroid autoimmune diseases. Clinical Immunology. 2017; 183: 63-74

C.Virili, M. Centanni: “With a little help from my friends” - The role of microbiota in thyroid hormone metabolism and enterohepatic recycling. Molecular and Cellular Endocrinology.2017; 458: 39-43

H. Karakuła-Juchnowicz, H. Pankowicz, D. Juchnowicz, J.L.V. Piedra, T. Małecka-Massalska: Intestinal microbiota – a key to understanding the pathophysiology of anorexia nervosa?. Psychatr. Pol. 2017; 51(5): 859-870.



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1223 Journal of Education, Health and Sport eISSN 2391-8306 7

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