Condition of the hemostatic system in pregnant women with the threat of premature birth when using metabolic therapy

E. A. Panchuk


130 pregnant women were examined with the threat of premature birth in the gestational age of 28-34 weeks: I group – 67 pregnant women with threatened preterm labor who received standard complex therapy in combination with metabolic therapy in the form of 300 mg of omega-3 polyunsaturated fatty acidsper day, group II - 63 pregnant women with threatened preterm labor who received only standard complextherapy. Analyzing the state of the hemostasis system, the following changes were revealed: an increase in the level of fibrinogen and prothrombin time, indicating a hypercoagulative process.Were observed a decrease in fibrinogen level, an increase in platelet count and activated partial thromboplastin time and a decrease in prothrombin time after treatment with the use of metabolic therapy, indicating the antithrombotic and antiaggregatory effects of metabolic therapy.


preterm labor; hemostasis system; metabolic therapy

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Reznichenko GI Prevention of miscarriage of pregnancy and preterm labor / GI Reznichenko // Woman's doctor. - 2013. - №3. - P. 10-14.

Makarov I.O. Possibilities of application of magnesium sulfate as a neuroprotector in the development of pre-term labor / IO Makarov, E.I. Borovkova // Obstetrics, gynecology and reproduction. - 2013. - Т.7, №1.- p. 41-44.

Blencowe H. National, regional, and global estimates of preterm birth rates in the year 2010 with time trends from 1990 for selected countries: a systematic analysis and implications / H.Blencowe, S.Cousens, M.Oestergaard [et al. ] // The Lancet. - June 2012. - Vol.379 (9832). - p. 2162 - 2172.

Dubik L.V. The role of the hemostasis system in the pathogenesis of reproductive losses (review of literature) / L.V. Dubik, O.M. Yuzko // Bukovinsky Medical Bulletin. - 2017. - Т.21, №2 (82). - P.134-136.

Lysenkov S.P. Emergency states and anesthesia in obstetrics. Clinical Pathophysiology and Pharmacotherapy / SP Lysenkov, VV Myasnikova, V.V. Ponomarev - SPb .: LLC Elby-SPb, 2014. - 600 p.

Makatsaria AD Antiphospholipid syndrome - immune thrombophilia in obstetrics and gynecology / AD Makatsaria, VO Bitsadze, SM Baimurodova [and others]. - Moscow: Triad-X, 2007. - 456 p.

Order of the Ministry of Health of Ukraine dated December 31, 2004 №676 "On approval of clinical protocols for obstetric and gynecological care", section "Preterm labor" and amendments to it №624 dated 03.11.2008.



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