Possibilities of using platelet-rich plasma in medicine, cosmetology and veterinary medicine. Review article.

Sylwia Wanda Uniejewska


Platelet rich plasma (PRP) is an autologous preparation obtained from blood. It has an increased number of platelets, and thus a high concentration of growth factors involved in the tissue renewal of the body. Platelet rich plasma is currently widely used in medicine, cosmetology and veterinary medicine. The method of obtaining PRP and an overview of its most common applications is presented below.


platelet-rich plasma, PRP use, PRP types, platelet-rich plasma effect, production method.

Full Text:



Marx R.E. Platelet-rich plasma: evidence to support its use. J. Oral Maxillofac. Surg. 2004; 62: 489–496.

Foster T.E., Puskas B.L., Mandelbaum B.R., Gerhardt M.B., Rodeo S.A. Platelet-rich plasma: from basic science to clinical applications. Am. J. Sports Med. 2009; 37: 2259–2272.

Eppley B.L., Woodell J.E., Higgins J. Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing. Plast. Reconstr. Surg. 2004; 114: 1502–1508.

Lyras D.N., Kazakos K., Agrogiannis G. i wsp. Experimental study of tendon healing early phase: is IGF-1 expression influenced by platelet rich plasma gel? Orthop. Traumatol. Surg. Res. 2010; 96: 381–387.

Harrison S., Vavken P., Kevy S. i wsp. Platelet activation by collagen provides sustained release of anabolic cytokines. Am. J. Sports Med. 2011; 39: 729–734.

Castillo T.N., Pouliot M.A., Kim H.J., Dragoo J.L. Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems. Am. J. Sports Med. 2011; 39: 266–271.

Cieślik-Bielecka A., Bielecki T., Gaździk T.S. i wsp. Autologous platelets and leukocytes can improve healing of infected high-energy soft tissue injury. Transfus. Apher. Sci. 2009; 41: 9–12.

Simonpieri A., Del C.M., Vervelle A. i wsp. Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 2: bone graft, implant and reconstructive surgery. Curr. Pharm. Biotechnol. 2012; 13: 1231–1256.

Cieślik-Bielecka A., Choukroun J., Odin G., Dohan Ehrenfest D.M. L-PRP/L-PRF in esthetic plastic surgery, regenerative medicine of the skin and chronic wounds. Curr. Pharm. Biotechnol. 2012; 13: 1266–1277.

Ferrari M., Zia S., Valbonesi M. i wsp. A new technique for hemodilution, preparation of autologous platelet-rich plasma and intraoperative blood salvage in cardiac surgery. Int. J. Artif. Organs 1987; 10: 47–50.

Serraino G.F., Dominijanni A., Jiritano F. I wsp. Platelet-rich plasma inside the sternotomy wound reduces the incidence of sternal wound infections. Int. Wound J. 2013 May 21. doi: 10.1111/iwj. 12087 [submitted to printing].

Schaaf H., Streckbein P., Lendeckel S. i wsp. Sinus lift augmentation using autogenous bone grafts and platelet-rich plasma: radiographic results. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2008; 106: 673–678.

McAleer J.P., Kaplan E., Persich G. Efficacy of concentrated autologous platelet-derived growth factors in chronic lower-extremity wounds. J. Am. Podiatr. Med. Assoc. 2006; 96: 482–488.

Fanning J., Murrain L., Flora R. i wsp. Phase I/II prospective trial of autologous platelet tissue graft in gynecologic surgery. J. Minim. Invasive Gynecol. 2007; 14: 633–637.

Cook J.L., Purdam C.R. Is tendon pathology a continuum? A pathology model to explain the clinical presentation of load-induced tendinopathy. Br. J. Sports Med. 2009; 43: 409–416.

de Vos R.J., Weir A., van Schie H.T. i wsp. Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial. JAMA 2010; 303: 144–149.

Peerbooms J.C., Sluimer J., Bruijn D.J., Gosens T. Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-year follow-up. Am. J. Sports Med. 2010; 38: 255–262.

Krogh T.P., Fredberg U., Stengaard-Pedersen K. i wsp. Treatment of lateral epicondylitis with platelet-rich plasma, glucocorticoid, or saline: a randomized, double-blind, placebo-controlled trial. Am. J. Sports Med. 2013; 41: 625–635.

Kon E., Buda R., Filardo G. i wsp. Platelet-rich plasma: intra-articular k nee injections produced favorable results on degenerative cartilage lesions. Knee Surg. Sports Traumatol. Arthrosc. 2010; 18: 472–479.

Patel S., Dhillon M.S., Aggarwal S., Marwaha N., Jain A. Treatment with platelet-rich plasma is more effective than placebo for knee osteoarthritis: a prospective, double-blind, randomized trial. Am. J. Sports Med. 2013; 41: 356–364.

Nin J.R., Gasque G.M., Azcarate A.V., Beola J.D., Gonzalez M.H. Has platelet-rich plasma any role in anterior cruciate ligament allograft healing? Arthroscopy 2009; 25: 1206–1213.

Adamski Z., Kaszuba A., editors. Dermatologia dla kosmetologów. Wrocław, Elsevier Urban & Partner 2010.

Callan A., Zdrowa skóra. Kraków, Wydawnictwo Medycyna Praktyczna 1999.

Bielecki T , Gazdzik TS, Arendt J et al. Antbacterial effect of autologous platelet gel enrich with growth factors and other active substances. In vitro study. J Bo Surg Br 2007; 89 :417-420.

Kim J., Park C., Park H.: Curative effect of autologous platelet-rich plasma on a large cutaneous lesion in a dog. Vet. Dermatol. 2009, 2, 123-126.

Kostrzewski M., Aleksiewicz R., Kostrzewa D., Kostro K., Lutnicki K.: The use of hyaluronic acid and autologous platelet-rich plasma in canine degenerative knee joint disease and anterior cruciate ligment injury. Wet. Prakt. 2013, 4, 16-24

Pietramaggiori G., Schrerer S., Cervi D., Klement G., Orgill D.: Tumors stimulate platelet delivery of angiogenic factors in vivo. An unexpected benefi. Am. J. Pathol. 2008, 9, 1609-1616.

Gołas A., Treliński J., Kliniczne zastosowanie osocza bogatopłytkowego, Hematologia 2014; 5: 256.

DOI: http://dx.doi.org/10.5281/zenodo.2529166


  • There are currently no refbacks.

Copyright (c) 2018 © The Authors

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014


POL-index 2011 - 2014


BASE 2011 - 2014




Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI


Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland






Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.


ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski