The role of intestinal dysbiozis in infringement of the function of the liver of rats after antibiotic therapy

A. V. Bocharov, O. A. Makarenko, L. I. Semik, T. V. Gladky, A. V. Maykova

Abstract


In experimental work on rats was shown that antibiotics with the most pronounced hepatotoxic effects contribute more to the development of dysbiosis of the colon and to an increase in serum urease activity. On the basis of the results obtained, an assumption was made of the hepatotoxic effect of urease on the pathogenic microbiota of the intestine.

Keywords


antibiotics, dysbiosis of intestinal, urease, liver

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References


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DOI: http://dx.doi.org/10.5281/zenodo.1889338

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