Distribution of “model” congenital malformations in children whose mothers used to live in the environmentally unfavorable areas

Olena Vlasova, Iryna Lastivka

Abstract


Abstract. To determine the frequency of “model” congenital malformations in children whose mothers used to live in places with different geochemical characteristics in Chernivtsi and to define the risk indices of their formation.
Material and methods. Retrospective analysis was carried out on 117 protocols of dissections of newborns and fetuses with CM, who died in utero or after birth in 2004-2014 in Chernivtsi and 489 genetic records of children born in Chernivtsi with “model” birth defects were also analyzed.
Results. A ten-year analysis showed that the frequency of “model” CM in Chernivtsi in general corresponds to the EUROCAT International Register indices, with the exception of multiple birth defects, which exceeded the European index by 2.4 times, hypospadias – by 6 times, and congenital hydrocephalus , the index of which was on the upper limit.
Conclusions. A significant risk of the formation of birth defects of the heart, the central nervous system and the genitourinary system was detected in the structure of “model” congenital malformations, provided that the mothers lived in places of geochemical disadvantages. The mortality of males with congenital malformations was higher than that of female children.

Keywords


heavy metals; pollution; developmental defects; newborns.

Full Text:

PDF

References


References

Congenital Anomalies and Public Health. 2017 http://www.eurocat-network.eu

Eduardo E. Castilla, Hebe Campala, Jorge S. Lоpez Camelo, and the ECLAMC ECOTERAT Group. Economic Activity and Congenital Anomalies: An Ecologic Study in Argentina. Environmental Health Perspectives. 2000; 108, 3: 192-7.

Jenkins KJ, Correa A, Feinstein JA, et al. Noninherited risk factors and congenital cardiovascular defects: current knowledge: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation.2007;115(23):2995–3014. doi: 10.1161/CIRCULATIONAHA.106.183216.

Bokonbaeva SD, Aldasheva NM, Lobzova AV, Dzhanabilova GA. Vrozhdennye poroki razvitija kak indikator kachestva sostojanija okruzhajushhej sredy. Vestnik KRSU.2008;8(4):105-10.

Lanovenko O. Rehionalnyi monitorynh pryrodzhenykh vad rozvytku v Khersonskii oblasti. Visnyk Lvivskoho universytetu seriia biolohichna. 2013: 1-10 http://hdl.handle.net/123456789/358

Corsello G, Giuffrè M. Congenital malformations. Matern Fetal Neonatal Med.2012; 25(1):25-9. doi: 10.3109/14767058.2012.664943.

EUROCAT. Instruction for the registration and surveillence of congenital anomalies. 2005 http://www.eurocat.ulter.ac.uk./ pub. data

Gubler EV., Genkin AA.. Primenenie neparametricheskih kriteriev statistiki v mediko-biologicheskih issledovaniyah [Application of nonparametric statistical criteria in biomedical research]. Leningrad: Medicina; 1973.140 s. (in Russian).

Fletcher R, Fletcher S, Vagner EH. Klinicheskaya ehpidemiologiya. Osnovy dokazatel'noj mediciny [Clinical epidemiology. Fundamentals of Evidence-Based Medicine.].Мoskva: Mediasfera; 2004. 352 s. ( in Russian).




DOI: http://dx.doi.org/10.5281/zenodo.1482917

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2018 © The Author (s) 2018

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 2011: 5.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)