The role of connective tissue metabolic processes in the development of pathological processes at inflammation of different intensity in parodontium

V. F. Cheremisina

Abstract


The objective. To study metabolic processes in connective tissue (CT) at different intensity of inflammation in parodontium. Materials and methods. The research is conducted on the sample of oxyproline, which is one of the indicators in the study of metabolic processes in the CT. This amino-acid presents in the blood in the free state, reflects the processes of collagen degradation in the form of protein-binding oxyproline and has no unambiguous interpretation. Results. At low intensity of the imflammation in the periodontium (stomatitis and alveolitis), the synthesis and collagen degradation are in relative equilibrium, and an increase in its intensity (gingivitis and especially periodontitis) leads to its violation. Conclusions. It has been established that the CT plays an important role in the development of pathological processes in periodontal tissues. The concentration of free and peptide-linked oxyproline in serum is higher in the groups of patients with more severe periodontal inflammation (periodontitis and gingivitis).

Keywords


oxyproline, connective tissue, periodontal tissue

Full Text:

PDF

References


Volkova M.N. (2009). Immunological mechanisms of pathogenesis of inflammatory periodontal diseases. Vestnik VGMU,8(3), 1-15.

Sharaev P.N., Botinkova E.A., Ivanova V.M. & etc. (1990). Determination of free and bound hydroxyproline in the urine. Lab. Delo, 12, 23-25.

Levitskii A.P., Makarenko O.A., Pochtar V.N. & etc. (2005). Visnyk stomatologii, 4, 7-10.

Gavrilov V.O., Luzin V.I., Gaidash D.I. (2011). Method of modeling of mandibular alveolitis in laboratory animals (rats): Patent for utility model of Ukraine № 61488621815 А, MPK. А61К6/00, 14, 10.

Levitskii A.P., Selyvanska T.O., Makarenko O.A. (2006). Method of modeling gingivitis. Patent 31011 Ukraine, MPK. А61Р 31/00А 61К35/66А 61С7/00. Applicant and patent holder: Institute of Dentistry, Academy of Medical Sciences of Ukraine. Bulletin 6, 3.

Peshkova L.V. (1997). Spontaneous lesion of periodontal tissues in rats under vivarium conditions, as a periodontitis model. Visnyk stomatologii, 2, 163-168.

General ethical principles of animal experiments: materially I Natsionalnogo kongressa po bioetike. (2001). NANU, 16.

Gubler E.V., Genkin A.A. (1973). Application of nonparametric statistical criteria in biomedical research. Meditsina, 141.




DOI: http://dx.doi.org/10.5281/zenodo.1468873

Refbacks

  • There are currently no refbacks.




Copyright (c) 2018 © The Author (s) 2018

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)