Pathophyisiology analysis overload nephron protein in the proximal tubule damage in the nephrolithiasis size stones of 0.6-1.0 sm

Yu. Ye. Rohovyi, O. I. Ariychuk, O. V. Gerush

Abstract


Nephrolithiasis as the most common urological disorder characterized by frequent early relapses, acquires a social character, because these patients are 30 to 45% of all urological patients, while in Europe the disease is diagnosed in 2% of the population. The study included 40 patients with nephrolithiasis, 10 patients constituted the control group. Set the “hidden” damage to the proximal nephron in the presence of renal stones with a size of 0.6-1.0 cm in the upper third of the ureter, the upper and middle sections of the calyx, which is confirmed by the inhibition of enzymatic fibrinolytic activity of urine, the presence of tubular proteinuria in the absence of inhibition of proximal reabsorption of sodium ions. The link “hidden” damage to the proximal tubule of the degree of overload of the proximal nephron is a protein graphics multicorrelation dependence between the protein concentration of urine, standardized excretion protein and excretion, which are becoming more significant disharmony form towards control in the following sequence: the upper third of the ureter, medium cup, top cup.

Keywords


nephrolithiasis, proteinuria, “latent damage of the proximal nephron”

Full Text:

PDF

References


Pishak VP, Gozhenko AI, Rohovyi YuYe. et [al] Rol katepsinu D kirkovoi rechovini nirok v prignicheni proksimalnoi reabsorbtii ioniv natriu za umov massivnoi proteinurii [The role of cathepsin D cortical substance of kidneys in the inhibition of proximal reabsorption of sodium ions under conditions of massive proteinuria]. Ukrainian medical almanac, 2000; 1: 135-138. (in Ukrainian).

Pishak VP, Gozhenko AI, Rohovyi YuYe. Tubulo-itersticiyniy sindrom [Tubulo-interstitial syndrome]. Chernivtsi: Medical Academy, 2002: 221. (in Ukrainian).

Rohovyi YuYe., Ariychuk OI. Pathophysiologichniy analys functii nirok za cystatinom C pri utvoreni nirkovich konkrementiv 0.6-1.0 cm pri likuvani apparatom litotriptor Duet Magna [Pahophysiological analysis of the renal function by cystatin C in the formation of renal stones 0.6-1.0 cm in size in conditions of treatment with apparatus litotriptor Duet Magna] J. of Education, Health and Sport.,2017;6:545-553. doi: http://dx.doi.org/10.5281/zenodo.822488 http://ojs.ukw.edu.pl/index.php/johs/article/view/4584 (in Ukrainian).

Boychuk TM, Rohovyi YuYe, Popovich GB. Pathophysiologia gepatorenalnogo syndroma pri gemichniy hypoksii [Pathophysiology of the hepatorenal syndrome in hemic hypoxia]. Chernivtsi: Medical University, 2012: 192. (in Ukrainian).

Gozhenko AI, Rohovyi YuYe, Fedoruk OS. et [al] “Prichovane” ushkodzenia proksimalnogo viddilu nephrona [The “hidden” damage of the proximal nephron]. Odessa med.j., 2001;5: 16-19. (in Ukrainian).

Rohovyi YuYe., Slobodian KV, Filipova LO. Patophysiologia vikovich osoblivostey funkcii nirok za umov nadlishku i deficitu ioniv natriu pri sulemoviy nephropatii [Pathophysiology of age characteristics of kidney function in conditions of excess and deficiency of sodium ions when Sublimate nephropathy]. Chernivtsi: Medical University, 2013: 200. (in Ukrainian).

Rohovyi YuYe., Zlotar OV, Filipova LO. Patophysiologia hepatorenalnogo sindromu na poliurichniy stadii sulemoviy nephropatii [Pathophysiology of hepatorenal syndrome on polunychne stage sublimate nephropathy] Chernivtsi: Medical University, 2012: 197. (in Ukrainian).




DOI: http://dx.doi.org/10.5281/zenodo.1250508

Refbacks

  • There are currently no refbacks.




Copyright (c) 2017 © The Author (s) 2017

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)