Parodontoprotective action of flavan- and lecithincontent hepatoprotectors on rats, which received the peroxide sunflower oil

A. I. Furdychko

Abstract


The aim. To determine parodontoprotective action of flavan- and lecithincontent hepatoprotectors on rats, which received the peroxide sunflower oil
The materials and methods. Quertulin (quercetin + inulin + citrate Ca), lekvin (lecithin + quercetin + inulin + Ca citrate) and lekasil (lecithin + flavolignan from Silybum marianum + Ca citrate) were used in doses 300 mg/kg every day during last 45 days. The peroxide sunflower oil introduced in dose 1 ml/rat every day during 75 days. The activity elastase, urease, catalase, lysozyme and content of malonic dialdehide (MDA) were determined in gingiva.
The findings. The inflammation and dysbiosis were developed into rat gingiva, which received the peroxide sunflower oil, but the activities of catalase and lysozyme were reduced. The introduction of quertulin, lekvin and lekasil reduced inflammation and dysbiosis, but raised the activities catalase and lysozyme.
Conclusion: The flavan- and lecithincontent means possess parodontoprotective action.

Keywords


gingiva, flavans, lecithin, peroxide substances of oils, inflammation, dysbiosis, antioxydante

Full Text:

PDF

References


Lushhak VI, Bagnjukova TV, Luzhna LI. Pokazniki oksidativnogo stresu. Peroksidi lіpіdіv: metodi [Indicators of oxidative stress. Lipid Peroxides: Methods]. Ukrai'ns'kyj biohimichnyj zhurnal, 2006;6:113–129. (in Ukrainian)

Osipenko AN, Akulich NV, Marochkov AV. Fatty acids and fatty aldehyds of blood as biochemical criterion of polyorgane insufficiency. Klinicheskaia laboratornaia diagnostika, 2012;10:113–129. (in Russian)

Li J, Li X, Cai W. et al. Comparison of different polar compounds-induced cytotoxicity in human hepatocellular carcinoma Hep G2 cell. Lipids Health. Dis., 2016;15(30):1–6.

Levitsky AP, Makarenko OA, Pochtar' VN et al. Perekisnaja model' stomatita [The peroxide model of stomatitis]. Visnyk stomatologii', 2005;4:7–10. (in Russian)

Vasyuk VL. Hepatoprotective action of flavancontent means at hepatopathy, caused by the peroxide sunflower oil. Visnyk mors'koi' medycyny, 2018;1:101-104. (in Russian)

Bocharov AV. Antiinflammation and antidysbiotic actions of flavancontent means on rat colon mucosa after received the peroxide sunflower oil. Journal Education, Health and Sport, 2017;7(6):1137-1144.

Tsepov LM. Prophylactic parodontology: from hypotheses to practice. Parodontologiya. 2000;1(15):16–18. (in Russian)

Moroz КА. The role peroxide lipids in the development parodontale pathology. Eksperymental'na ta klinichna fiziologija i biohimija, 2004;2:91–101. (in Ukrainian)

Dursunr E, Akalin FA, Gene T. et al. Oxidative stress and periodontal disease in obesity. Medicine (Baltimore), 2016;95(12):3136–3143.

Levitsky AP, Denga OV, Makarenko OA et al. Eksperimentalnye metody vosproizvedeniia gignivita: metodicheskie rekomendatsii [The experimental methods of gingivite reproduction: method guidelines]. Odessa, KP OGT, 2013: 15. (in Russian)

Voskresenskii ON, Zhutaev IA, Bobyrev IA. The antioxidante system, ontogenes and ageing. Voprosy meditsinskoi khimii, 1982;1:14–27. (in Russian)

Yarova SP, Osypenkova TS, Agafonova GJu et al. The peculiarities of antioxidant therapy at experimental parodontitis background normo- and hyporeactivity of organism. Ukrai'ns'kyj stomatologichnyj al'manah, 2002;5:23–26. (in Ukrainian)

Levitsky AP, Makarenko OA, Levchenko OM et al. Bioflavonoidnye gepatoprotektory [Bioflavonoid hepatoprotectors]. Odessa: KP OGT, 2014:86. (in Russian)

Levitsky AP, Makarenko OA, Selivanskaуa IA et al. The experimental prophylaxis of the peroxide periodontitis by antidysbiotic means. Journal of Education, Health and Sport. 2017;7(2):682–693.

Levitsky AP, Denga OV, Makarenko OA et al. Biokhimicheskie markery vospaleniya tkaney rotovoy polosti: metodicheskie rekomendatsii [Biochemical markers of inflammation of oral cavity tissue: method guidelines]. Оdеssа, KP OGT, 2010:16. (in Russian)

Levitsky AP, Makarenko OA, Selivanskaya IA et al. Fermentativnyy metod opredeleniya disbioza polosti rta dlya skrininga pro- i prebiotikov: metodicheskie rekomendatsii [Enzymatic methods for determination of oral dysbiosis for screening pro- and prebiotics: method guidelines]. Кiev, GFC, 2007: 22. (in Russian)

Levitsky AP, Makarenko OA., Denga OV et al. The experimental methods of restoration and estimation of the degree of dysbiosis in oral tissues. Visnyk stomatologii. 2010; 2:22–23. (in Russian)

Kokunin VA. Statistical processing of data for a small number of experiments. Ukrai'ns'kyj biohimichnyj zhurnal, 1975;47(6):776–791. (in Russian)




DOI: http://dx.doi.org/10.5281/zenodo.1250090

Refbacks

  • There are currently no refbacks.




Copyright (c) 2017 © The Author (s) 2017

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)