The pathogenetic basis of correlation secretion thyroids hormons with progress and prognosis chronic obsructive pulmonary disease (COPD)

N. A. Matsegora, O. E. Shpota


We has been studied influence of thyroxine on functional thymalinum-dependence activity of T-cell-bound immunity. It was established that preincubation of T-lympocytes with physiological concentration of thyroxine led to pronounced thymalinum-dependence abolition of receptor field of T-lympocytes modification.
The syndrome of low triiodthyronine in patients with COPD is a kind of "factor of complication" of the course of the disease. It is due to the formation of a deeper disruption of reparative regeneration of the bronchial epithelium (including procoagulant and fibrinolytic activity of epithelial cells) and aggravation of immune disbalance.


thyroxine, triiodthyronin, thymalinum, chronic obstructive pulmonary disease (COPD)

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