The pathogenetic basis of correlation secretion thyroids hormons with progress and prognosis chronic obsructive pulmonary disease (COPD)

N. A. Matsegora, O. E. Shpota

Abstract


We has been studied influence of thyroxine on functional thymalinum-dependence activity of T-cell-bound immunity. It was established that preincubation of T-lympocytes with physiological concentration of thyroxine led to pronounced thymalinum-dependence abolition of receptor field of T-lympocytes modification.
The syndrome of low triiodthyronine in patients with COPD is a kind of "factor of complication" of the course of the disease. It is due to the formation of a deeper disruption of reparative regeneration of the bronchial epithelium (including procoagulant and fibrinolytic activity of epithelial cells) and aggravation of immune disbalance.

Keywords


thyroxine, triiodthyronin, thymalinum, chronic obstructive pulmonary disease (COPD)

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References


Jdan V.M. Vicoristannya statiniv pri comorbidnoyi patologii u praktici simeynogo lykarya [The use of statins in comorbid pathology in the practice of a family doctor] / Jdan V.M, Potyajenko M.M., Sokoaymenova G.S. // Simeyna medicina. – 2015. – №3(59). – S. 145-147. (in Ukrainian)

Ovcharenko S.I. Evoluziya po globalnoj iniciative k chronicheskim obstruktivnim zabolevaniyam legkikh i niviy podhod k protivovospalitelnoy terapii [Evolution of the Global Initiative on Chronic Obstructive Pulmonary Disease and a New Approach to Anti-Inflammatory Therapy ] / C.I. Ovcharenko, Ya. K. Galetskayte //Lechashiy vrach. . – 2014. - №1. – S. 46 – 48.(in Russian).

Feshchenko Yu. I. Сhronicheskiу obstruktivniу zabolevaniya legkikh: etiologia, patogenez, klassifikaciya, diagnostika i terapia [Chronic obstructive pulmonary disease: etiology, pathogenesis, classification, diagnosis, therapy : materials of the congress. ] /Yu. I. Feshchenko, L. A. Yashina, O. Ya. Dzlyublik [and others] //. - 2013. - No. 3. - Dodatok. - S. 7-12. (in Ukrainian).

Todorko L.D. Diferentsiyne zastosuvannya bronchodilatatorov y litnich ludey [Differential application of bronchodilators in the treatment of COPD in older people] / Todorko L.D/ // Clinichna immunologia, allergologia, infectologia. - 2011.-No. 3. -S. 83-86. (in Ukrainian).

Todoriko L.D. Funktsionalni zmini shchitopodibnoyi zalzi,thireotropna funkziya hipophizu, ta diya cortizolu pri chronicheskim obstruktivnim zabolevaniyam legkikh [Functional changes of the thyroid gland, thyrotropic pituitary function and the effect of cortisol in chronic obstructive pulmonary disease in older patients.] / Todoriko L. D. // Ukrainsky pulmonologichniy journal. - 2008 - No. 2. -S.113-116. (in Ukrainian).

Anzueto A. The pathogenesis of acute infection in COPD. Breathe 2009; 5: 311–315.

Aaron S.D., Donaldson G.C., Whitmore G.A. et al. Time course and pattern of COPD exacerbation onset. Thorax 2012; 67: 238–243.

Barnes P.J. Chronic obstructive pulmonary disease: molecular and cellular mechanisms / P.J. Barnes, S.D. Shapiro, R.A. Pauwels // Eur. Respir. J. – 2003. - Vol. 22. – p. 672-688.

Baty F.Comorbidities and Burden of COPD: A Population Based Case-Control Study / Baty F., Putora P.M., Isenring B. [et al.] // Plos one. – 2013. – Vol.8

Brashier B.B. Risk Factors and Pathophysiology of Chronic Obstructive Pulmonary Disease (COPD) / B.B. Brashier, R. Kodgule //JAPI. – 2012. - Vol.60 – Suppl. – p.17-21.

Bednarek M., Maciejewski J., Wozniak M., Kuca P., Zielinski J. Prevalence, severity and underdiagnosis of COPD in the primary care setting // Thorax. — 2008. — 63(5). — 402¬7. doi: 10.1136/thx.2007.085456[published Online First: Epub Date]. 

Decramer M. Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial / M. Decramer, B. Celli, S. Kestenat al. // Lancet. – 2009. – Vol. 374. – p. 117.

Divo M. Comorbidities and Risk of Mortality in Patients with Chronic Obstructive Pulmonary Disease / M. Divo, C. Cote, J.P. de Torres, C. Casanova, J.M. Marin[et al.] // Am. J. Respir. Crit. Care Med. – 2012. – Vol. 186. – p. 155–161.

Echave-Sustaeta J.M. Comorbidity in chronic obstructive pulmonary disease. Related to disease severity? / J.M.Echave-Sustaeta, L.Comeche Casanova, B.G.Cosio[et al.] // Int. J. Chron. Obstruct. Pulmon. Dis. 2014. – Vol. 9. – p. 1307-1314.

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Global Initiative for Chronic Obstructive LungDisease (GOLD) 2016. Updated 2016.

Halbert R.J., Natoli J.L., Gano A., Badamgarav E., Buist A.S., Mannino D.M. Global burden of COPD: systematic review and meta¬analysis // The European respiratory journal: official journal of the European Society for Clinical Respiratory Physiology. — 2006. — 28(3). — 523¬32. doi: 10.1183/09031936.06.00124605[published Online First: Epub Date]. 

Jones P.W. (2013). COPD assessment test --rationale, development, validation and performance / P.W. Jones // J. COPD. – 2013. – Vol.10. -№ 2. P. 269-271.

Mathers C.D. Projections of Global Mortality and Burden of Disease from 2002 to 2030 / C.D. Mathers, D. Loncar // PLoS Med. – 2006. –Vol.3. - № 1. – p. e442.

Miravitlles M. Comorbidities of patients in tiotropium clinical trials: comparison with observational studies of patients with chronic obstructive pulmonary disease / M. Miravitlles, D. Price, K.F. Rabe [et al.] // Int. J. Chron. Obstruct. Pulmon. Dis. – 2015. – Vol. 10. – p. 549-564.

Suissa S., Dell'aniello S., Ernst P. Longterm natural history of chronic obstructive pulmonary disease: severe exacer bations and mortality. Thorax 2012; 67: 957–963.

Viegi G. Definition, epidemiology and natural history of COPD. Series ‘‘comprehensive management of end-stage COPD’’ Edited by N. Ambrosino and R. Goldstein Number 1 in this Series / G. Viegi, F. Pistelli, D.L. Sherrill [et al.] // Eur.Respir.J. – 2007. – Vol. 30. – p. 993-1013.

Zwar N.A. Predictors of accuracy of diagnosis of chronic obstructive pulmonary disease in general practice / N.A. Zwar, G.B. Marks, O. Hermiz, [et al.] // Med. J. Aust. – 2011. – Vol. 195. - №4. – p. 168-171.




DOI: http://dx.doi.org/10.5281/zenodo.1238873

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