Quality of life of patients treated with radiotherapy

Adrianna Rożniecka-Hełmińska, Diana Karolina Maniak, Ewa Kupcewicz

Abstract


Abstract: Radiotherapy is one of the most commonly used anticancer treatments. Despite continuous technological development it may cause adverse symptoms, and as a result reduce the quality of life in patients undergoing radiation therapy.

Objective of the work: Analysis of the quality of life of patients treated with radiation therapy and the effect determination of selected factors and their clinical complications on the quality of life of oncological patients.

Material and methods: The study included 100 patients diagnosed with cancer, including 47 (47%) women and 53 (53%) men, with an average age of 62.1 (± 9.47) years. The study used a standardized questionnaire EORTC QLQ-C30, in assessing the quality of life of cancer patients and a questionnaire of our own design containing sociodemographic and clinical data. The collected empirical data were analyzed statistically. The level of significance was p <0.05.

Results: In the group of patients tested the average rate the overall quality of life was 50.5 (± 16.28) with a median of 50. The highest quality of life in the test reported in the field of cognitive functioning, and the lowest in the area of social functioning. In 72% of patients experienced complications of radiotherapy. During the analysis, it was found that the overall quality of life and functioning in all domains is lower comparing to the results of patients with no side effects of treatment. The analysis also found that in patients with head and neck cancer, which are irradiated at the same area, the level of cognitive functioning is significantly lower than the level of functioning in the same domain patients irradiated in the chest area (p <0.008) and in the area of reproductive organs (p <0.007).

Conclusions: There is a diversity of quality of life of patients with and without complications of treatment with ionizing radiation, which have a significant impact on the quality of life of cancer patients. Location area irradiated during radiotherapy has a significant impact on the quality of life of patients. Treatment with radiation therapy adversely affects the quality of life of patients.


Keywords


cancer, oncological treatment, ionizing radiation, quality of life, complications of radiotherapy

Full Text:

PDF

References


Yucel B, Akkaş EA, Okur Y, Eren AA, Eren MF, Karapinar H, Babacan NA, Kiliçkap S. The impact of radiotherapy on quality of life for cancer patients: a longitudinal study, Support Care Cancer 2014; 22(9): 2479-87. doi: 10.1007/s00520-014-2235-y.

Bottomley A. The cancer patient and quality of life. Oncologist. 2002; 7(2): 120-5.

Stańczyk MM. Music therapy in supportive cancer care. Rep Pract Oncol Radiother 2011; 16(5): 170-172.

Wojciechowska U, Olasek P, Czuderna K, Didkowska J. Nowotwory złośliwe w Polsce w 2014 roku. Krajowy Rejestr Nowotworów MZ 2016; 11-17.

Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015; 65(2): 87-108. doi: 10.3322/caac.21262.

Osuch-Wójcikiewicz E, Bruzgielewicz A. Powikłania po radioterapii nowotworów głowy i szyi. Otolaryngologia 2010; 9(1): 1-6.

Habets EJ, Dirven L, Wiggenraad RG, Verbeek-de Kanter A, Lycklama À Nijeholt GJ, Zwinkels H, Klein M, Taphoorn MJ. Neurocognitive functioning and health-related quality of life in patients treated with stereotactic radiotherapy for brain metastases: a prospective study. Neuro Oncol. 2016; 18(3): 435-44. doi: 10.1093/neuonc/nov186.

Tuschy B, Berlit S, Romero S, Sperk E, Wenz F, Kehl S, Sütterlin M. Clinical aspects of intraoperative radiotherapy in early breast cancer: short-term complications after IORT in women treated with low energy x-rays. Radiat Oncol. 2013; 22; 8: 95. doi: 10.1186/1748-717X-8-95.

CM van Rij, WD Oughlane-Heemsbergen, AH Ackerstaff, EA Lamers, AJM Balm, CRN Rasch. Parotid gland sparing IMRT for head and neck cancer improves xerostomia related quality of life. Radiat Oncol. 2008; 3: 41. doi: 10.1186/1748-717X-3-41.

Żmijewska-Tomczak M, Milecki P, Olek-Harb K, Hojan K, Golusiński W, Rucińska A, Adamska A. Factors influencing quality of life in patients during radiotherapy for head and neck cancer. Arch Med Sci 2014; 10(6): 1153-59.

Dirix P, Nuyts S, Vander Poorten V, Delaere P, Van den Bogaert W. The influence of xerostomia after radiotherapy on quality of life: results of a questionnaire in head and neck cancer. Support Care Cancer. 2008; 16(2): 171-9. doi: 10.1007/s00520-007-0300-5

Provencher S, Oehler C, Lavertu S, Jolicoeur M, Fortin B, Donath D. Quality of life and tumor control after short split-course chemoradiation for anal canal carcinoma. Radiat Oncol. 2010; 23(5): 41. doi: 10.1186/1748-717X-5-41.

Löfdahl E, Berg G, Johansson KA, Leonsson Zachrisson M, Malmgren H, Mercke C, Olsson E, Wiren L, Johannsson G. Compromised quality of life in adult patients who have received a radiation dose towards the basal part of the brain. A case-control study in long-term survivors from cancer in the head and neck region. Radiation Oncology 2012; 7: 179. doi. 10.1186/1748-717X-7-179.

Braam PM, Roesink JM, Raaijmakers CPJ, Busschers WB, Terhaard CHJ. Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy. Radiation Oncology 2007; 2(1): 3. doi: 10.1186/1748-717X-2-3. ·

Yu Y, Hu L, Chen X, Ge M, Zhu H, Yan Y. The Impact of the Predictive Nursing Education Process on Degree of Comfort and Quality of Life for Patients in the Oncology Department. Iran J Public Health 2017; 46(9): 1231-36.

Scott C, Suh J, Stea B, Nabid A, Hackman J. Improved survival, quality of life, and quality-adjusted survival in breast cancer patients treated with efaproxiral plus whole brain radiation therapy for brain metastases. Am J Clin Oncol 2007; 30(6): 7-570.

Steinmann D, Paelecke-Habermann Y, Geinitz H, Aschoff R, Bayerl A, et al. Prospective evaluation of quality of life effects in patients undergoing palliative radiotherapy for brain metastases. BMC Cancer 2012; 12: 283. doi: 10.1186/1471-2407-12-283

Muthny FA, Koch U, Stump S. Quality of life in Oncology Patients. Psychother Psychosom 1990; 54: 145-160.

King MT. The interpretation of scores from the EORTC quality of life questionnaire QLQ-C30. Qual Life Res 1996; 5: 67-555.

Osoba D, Rodrigues G, Myles J, Zee B, Pater J. Interpreting the significance of changes in health-related quality of life scores. J Clin Oncol 1998; 6:44-139.

Bjordal K, Ahlner-Elmqvist M, Hammerlid E, Boysen M, Evensen JF, Biörklund A, Jannert M, Westin T, Kaasa S. A prospective study of quality of life in head and neck cancer patients. Part II: Longitudinal data. Laryngoscope 2001; 111(8): 1440-52. doi: 10.1097/00005537-200104000-00021.

Budischewski K, Fischbeck S, Mose S. Quality of life of breast cancer patients in the course of adjuvant radiotherapy. Support Care Cancer 2008; 16: 299–304.

Bansal M, Monanti BK, Shah N, Chaudhry R, Bahadur S, Shukla NK. Radiation related morbidities and their impact on quality of life in head and neck cancer patients receiving radical radiotherapy. Qual Life Res 2004; 13: 481–488.

De Graeff A, de Leeuw JRJ, Ros WJG, Hordijk GJ, Blijham GH, Winnubst JAM. Long-term quality of life of patients with head and neck cancer. Laryngoscope 2000; 110(1): 98–106.

Xiao C, Miller AH, Felger J, Mister D, Liu T, Torres MA. A prospective study of quality of life in breast cancer patients undergoing radiation therapy. Adv Radiat Oncol 2016; 1(1): 10-16. doi: 10.1016/j.adro.2016.01.003.

Fernandez G, Pocinho R, Travancinha C, Netto E, Roldão M. Quality of life and radiotherapy in brain metastasis patients. Rep Pract Oncol Radiother. 2012; 17: 281–287.

Hutnik M, Składowski K, Wygoda A, Rutkowski T, Pilecki B. Dawki tolerancji dla narządów krytycznych w radioterapii chorych na raka głowy i szyi. NOWOTWORY Journal of Oncology 2013; 63(1): 35–47.

Jereczek-Fossa BA, Marsiglia RH, Orecchia R. Radiotherapy-related fatigue. Critical Reviews in Oncology/Hematology 2002; 41: 317–325.




DOI: http://dx.doi.org/10.5281/zenodo.1201558

Refbacks

  • There are currently no refbacks.




Copyright (c) 2018 © The Author(s)

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)