Insulin-resistance and lipids metabolism in women at menopause

Marina Dmitrуina Gresko, Tatyana Sergуivna Bulik, Larisa Vasylivna Rynzhuk, Vasyl Yefremovych Rynzhuk, Olexandra Ahdriivna Palamariuk, Olesia Yuriivna Vovk

Abstract


The article describes lipid metabolism in women during premenopausal and considered their relationship with the level of insulin sensitivity and abdominal obesity. Examined 20 women aged 46-48 years, with fixed transition to pre-menopause on the bases of menstrual cycle dysfunction or amenorrhea during a year as well as a decrease of visualized follicular reserve according to the results of ultrasonic examination of the organs of the small pelvis, were involved into investigation. Body mass increase with abdominal obese formation and disorders of the lipid metabolism against a background of insulin resistance is observed in women during pre-menopause against a background of sexual hormones deficiency.


Keywords


lipid metabolism, abdominal-visceral obesity, insulin resistance, perimenopause.

Full Text:

PDF

References


Бутрова С. А. Метаболический синдром: патогенез, клиника, диагностика, подходы к лечению / Бутрова С. А. // Русский медицинский журнал. – 2001. – № 2. – С. 56–60. (Butrova S.A. (2001). Metabolicheskii sindrom: patogenes, klinika, diagnostic, podhody k lecheniyu [Metabolic syndrome: pathogenesis, clinical picture, diagnostics, approaches to the treatment / Butrova S.A. // Russian medical journal. – 2001. - № 2. - P. 56-60. in Russian].).

Григорян О. Р. Менопаузный синдром у женщин с нарушениями углеводного обмена. Взгляд гинеколога-эндокринолога / Григорян О. Р., Андреева Е. Н. // Трудный пациент. – 2007. – № 9. – С. 29 – 34. (Grigorian O.R. (2007). Menopauznyisindrom u zhenshchin s narusheniyamiuglevodnogoobmena. Vzgliad gineko-loga-endokrinologa [Menopause syndrome in women with carbohydrate metabolism disorder. Point of view of gynecologist-endocrinologist / Grigorian O.R., Andreeva E. N. // Hard patient. – 2007. -№ 9. – P. 29-34. in Russian].).

Григорян О. Р. Заместительная гормональная терапия у женщин, больных сахарным диабетом, в период пери- и постменопаузы: руководство для врачей / Григорян О. Р., Анциферов М. Б. – М., 2001. – С. 15–16. (Grigorian O.R. Menopauznyisindrom u zhenshchin s narusheniyamiuglevodnogoobmena. Vzgliad gineko-loga-endokrinologa [Grigorian O.R. Grigorian O.R. (2001) Substituting hormonal therapy in women suffering from diabetes mellitus in pre- and postmenopausal period: guidance for doctors / Grigorian O.R., Antsyferov M.B. – M., 2001. – P. 15-16. . in Russian].).

Дубоссарская З. М., Дубоссарская Ю. А. Репродуктивная эндокринология (перинатальные, акушерские и гинекологические аспекты): Учебно-метод. пособ.. – Д.: Лира ЛТД, 2008. – 416 с. (Dubossarskaya Z.M., Dubossarskaya Yu. A. (2008). Reproductive endocrinology - (perinatal, obstetrics and gynecological aspects) [Dubossarskaya Z.M., Dubossarskaya Yu. A. Reproductive endocrinology - (perinatal, obstetrics and gynecological aspects): Educational-methodical textbook. – D.: Lira LTD, 2008. – 416 p. in Russian].).

Ефименко О. А. Пременопауза – предчувствие осени / Ефименко О. А. // Здоров’я України. – 2009. – Тематичний номер. – С. 60–62. (Efimenko O.A. (2009). Premenopauza – predchuvstvie oseni [Pre-menopause – presentiment of senility / Efimenko O.A. // Health of Ukraine. – 2009. – Subject issue. – P. – 60-62.in Russian].).

Медицина климактерия / Под. ред. Сметник В. П. – Ярославль: ООО «Издательство Литера», 2006. – 848 с. (Meditsyna I klimakteriya / Pod red. Smetnik V.P. (2006). [Climacteric medicine / Edited by Smetnik V.P Yaroslavl’: OOO “Publishing house Litera”, 2006. – 848 p. in Russian].).

Савельева Л. В. Современные подходы к лечению ожирения / Савельева Л. В. // Врач. – 2000. – № 12. – С. 12–14. (Savel’eva L.V.(2000). Sovremennye podhody k lecheniyu ozhyreniya [Savel’eva L.V. Sovremennyepodhody k lecheniyuozhyreniya / Savel’eva L.V. // Vrach. – 2000. - № 12. – S. 12-14. in Russian].).

Сметник В. П. Системные изменения у женщин в климактерии [Електронний ресурс] / Сметник В. П. // Русский медицинский журнал. – 2001. – № 9. – Режим доступу до журн.: http://www.rmj.ru/articles_1286.htm. (Smetnik V.P. (2001). Sistemnyeizmeneniya u zhenshchin v klimakterii [Electronnyiresurs] [Smetnik V.P. System changes in women in climacteric period [electronic resort] / Smetnik V.P. // Russian medical journal. – 2001. - № 9. – Access to the journal://www.rmj.ru/articles_1286.htm. in Russian].).

Bray G. A. Etiology and pathogenesis of obesity / Bray G. A. // Clinical Conerstone. – 1999. – Vol. 2. – P. 1–15.

Granberry M. C. The insulin resistance syndrome / Granberry M. C., Fonseca V. A. // Southern Medical Journal. – 1999. – vol. 92. – № 1. – Р. 2–14.

Krotkiewski M. Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution / Krotkiewski M., Bjorntorp P., Sjostrom L., Smith U. // J Chin Invest. – 1983. – vol. 72. – P. 1150–1162.

Poehlman E. T. Changes in energy balance and body composition at menopause: a controlled longitudinal study / Poehlman E. T., Toth M. J., Gardner A. W. // Ann Intern Med. – 1995. – vol. 123. – P. 673–675.

Poehman E. T. Traversing the menopause: changes in energy expenditure and body composition / Poehman E. T., Tchernof A. // Coronary Artery Dis. – 1998. – vol. – P. 799–803.

Shimokata H. Studies in the distribution of body fat: effects of age, sex and obesity / Shimokata H., Tobin J. D., Muller D. C. et al. // J Gerontol. – 1989. – vol. 44. – P. 66–73.

WHO. Obesity: preventing and managing the global epidemic // Report of a WHO Consultation. WHO Technical Report Series 894. – Geneva: World Health Organization, 2000.




DOI: http://dx.doi.org/10.5281/zenodo.1182719

Refbacks

  • There are currently no refbacks.




Copyright (c) 2018 © The Author (s) 2018

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)