Background. In the spite of the intensive search of effective ways to treat EM, there is no common concept in systemic therapy for EM, and the published data are fragmentary in nature

The purpose. Evaluation of epithelization of erosion and ulcers of the oral mucosa in patients with multiforme exudative erythema after the pathogenetically substantiated therapy have been done.

Results and conclusion. The following investigations show that the use of the pr4eparation "Solcoseryl" in combination with interferon or prednisolone allow to improve the metabolism of the epithelium of a mucous membrane of the oral cavity and to improve the processes of repair and regeneration of damaged tissues in patients with toxic-allergic and infectious-allergic forms of an exudative erythema multiforme.

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