Informativity of proteinograms as a clinical-diagnostic test at dispoteinemia in the age aspect

R. F. Yeriomenko, M. O. Ostapets

Abstract


The article analyzed dates of the usefulness of proteinograms as a clinical diagnostic test at dysproteinemia in age aspect. Established that proteinograms has  differences that depending on age, so these aspects should be considered in the diagnosis of certain pathological conditions in different age groups. Studying of children’s proteinograms in various pathological conditions indicates the appropriate changes in the fractional part of albumin and globulin, that characterized the development of inflammation and destruction of connective tissue. Besides diagnostic tests that help in the diagnosis, determine the stage of disease and the effectiveness of therapy is to study proteins "acute phase" and rheumatoid factor. Established the feasibility of proteinograms on the studying of dysproteinemia in different pathological conditions in adult age. It is found correlation between changes in protein fractions and stage of pathological process in connective tissue diseases (rheumatoid arthritis and systemic lupus erythema). At skin diseases, urinary, respiratory and hepatobiliary systems were recorded proteinograms changes depending on the damage of a system.

Analysis of the results allows more accurate founded the diagnosis, determine the stage of the pathological process and evaluate the effectiveness of the pharmacotherapy.


Keywords


proteinogramm, laboratory diagnostics, dysproteinemia, pathological condition

Full Text:

PDF

References


Biomarkers in clinical medicine / L. V. Pavlushkina, E. A. Chernevskaya, I. B. Dmitrieva [et al.] // Laboratory. – 2013. – № 3. – P. 10–14. (In Russian)

Velkov V. V. Biomarkers of neonatal sepsis: C-reactive protein, procalcitonin, presepsin / V. V. Velkov // Medical alphabet. . – 2016. – Vol. 2, № 13. – P. 9–20. (In Russian)

Velkov V. V. C-reactive protein in laboratory diagnostics / V. V. Velkov // Scientific and Practical Journal. – 2008. – № 2 (21). – P. 37–48. (In Russian)

Recurrent changes in the composition of proteins and chemiluminescent properties of donor blood serum / I. I. Rudneva, V. G. Shaida, E. N. Skuratovskaya [et al.] // Problems of Aging and Longevity. – 2013. – Vol. 22. – P. 71. (In Russian)

Gusev E. Yu. C-reactive protein: pathogenetic and diagnostic significance / E. Yu. Gusev // Ural Medical Journal. – 2014. – № 1 (115). – P. 113–121. (In Russian)

Diagnostic value of C-reactive protein in neonatal practice / M. P. Bondarenko, I. Orlov, M. Yu. Bondarenko [et al.] // Child health. – 2010. – № 2 (10). – P. 16–20. (In Ukrainian)

Kamyshnikov V. S. Clinical laboratory tests from A to Z and their diagnostic profiles / V. S. Kamyshnikov. – Minsk, Belarus, 2005. – 176 p. (In Russian)

Kamyshnikov V. S. Oncomarkers: methods of determination, reference values, interpretation of tests / V. S. Kamyshnikov. – M. : MEDpress-inform, 2011. – 128 p. (In Russian)

Kubanov S. I. The main aspects of laboratory diagnostics in urgent surgery / S. I. Kubanov, Yu. Yu. Pukhtin, A. B. Kubanova // Bulletin of the North-Caucasian Federal University. – 2014. – № 3 (42). – P. 85–86. (In Russian)

Kushkun A. A. Guide to laboratory diagnostic methods / A. A. Kushkun. – M.: GEOTAR-Media, , 2007. – 800 p. (In Russian)

Lifshits V. M. Biochemical analyzes in the clinic / V. M. Livshits, V. I. Sidelnikova. – 2 nd ed. – M.: Med. Inform. Agency, 2001. – 303 p. (In Russian)

Melentiev A. S. Laboratory diagnostic methods in the propaedeutic clinic / A. S. Melentiev, A. V. Strutynsky, Yu. Yu. Golubev. – M.: GBOU VPU RNIMU N. I. Pirogova, Ministry of Health of the Russian Federation, 2013. – P. 49–56. (In Russian)

Jackson A. P. Replication proteins and human disease / A. P. Jackson, R. A. Laskey, N. Coleman // Cold Spring Harbor Perspectives in Biology. – 2014. – Vol. 6. – P. 1–17.




DOI: http://dx.doi.org/10.5281/zenodo.399312

Refbacks

  • There are currently no refbacks.




Copyright (c) 2017 © The Author (s) 2017

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

Journal Language(s): English 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Instytut Kultury Fizycznej Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Institute of Physical Education Kazimierz Wielki University in Bydgoszcz, Poland 85-091 Bydgoszcz ul. Sportowa 2  www.ukw.edu.pl Copyright by Instytut Kultury Fizycznej UKW w Bydgoszczy http://ojs.ukw.edu.pl/index.php/johs  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

SIC Science citation index (calculated on the basis of TCI and Page Rank) 0

Russian Impact factor 0.16

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

The InfoBase Index IBI Factor for the year 2015 is 3.56 in InfoBase Index.com.

Website: www.infobaseindex.com

Universal Impact Factor 1.78 for year 2012. (http://www.uifactor.org/AppliedJournals.aspx)

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)