Inactivity and fatty liver disease

Marek Rác, Ľubomír Skladaný, Adam Szulc, Zuzana Mesárošová, Mária Szántová

Abstract


Physical activity represents a key element in the prevention and management of many chronic diseases. On other hand physical inactivity is a primary cause of obesity, metabolic syndrome and nonalcoholic liver disease. A higher body weight is associated with an increased incidence of a number of conditions, including diabetes mellitus, cardiovascular disease and nonalcoholic fatty liver disease. Obesity is associated with a increased risk of all-cause mortality. Hepatic consequence of sedentary lifestyle is nonalcoholic fatty liver disease (NAFLD), which is now in Western countries the most common cause of chronic liver disease. NAFLD primary affects hepatic structure and function. NAFLD cause morbidity and mortality from liver cirrhosis, liver failure and hepatocellular carcinoma. The majority of deaths among NAFLD patients are attributable to cardiovascular disease (CVD) and cancer. NAFLD is strongly associated with the clinical features of insulin resistance and is the hepatic component of metabolic syndrome.

Keywords


inactivity, obesity, metabolic syndrome, nonalcoholic fatty liver disease

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References


Flegal, K. M., Carroll, M. D., Kit, B. K. & Ogden, C. L. Prevalence of Obesity and Trends in the Distribution of Body Mass Index Among US Adults, 1999-2010. JAMA 307, 491 (2012).

Tsai, A. G., Williamson, D. F. & Glick, H. A. Direct medical cost of overweight and obesity in the USA: a quantitative systematic review. Obes. Rev. 12, 50–61 (2011).

Chalasani, N. et al. The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 55, 2005–2023 (2012).

Berzigotti, A. et al. Obesity is an independent risk factor for clinical decompensation in patients with cirrhosis. Hepatology 54, 555–61 (2011).

TRAN, T. T. et al. Living donor liver transplantation: Histological abnormalities found on liver biopsies of apparently healthy potential donors. J. Gastroenterol. Hepatol. 21, 381–383 (2006).

Pedrosa de Oliveira, C., Mahmud Saviero, S. & Strauss, E. Changes in histological criteria lead to different prevalences of nonalcoholic steatohepatitis in severe obesity. Ann. Hepatol. 6, 255–261 (2007).

Gholam, P. M., Flancbaum, L., Machan, J. T., Charney, D. A. & Kotler, D. P. Nonalcoholic Fatty Liver Disease in Severely Obese Subjects. Am. J. Gastroenterol. 102, 399–408 (2007).

Mazzotti, A., Caletti, M. T., Sasdelli, A. S., Brodosi, L. & Marchesini, G. Pathophysiology of Nonalcoholic Fatty Liver Disease: Lifestyle-Gut-Gene Interaction. Dig. Dis. 34, 3–10 (2016).

Adams, L. A. et al. The Natural History of Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study. Gastroenterology 129, 113–121 (2005).

Valenti, L. et al. Destined to develop NAFLD? The predictors of fatty liver from birth to adulthood. J. Hepatol. 0, 1218–1229 (2016).

Fassio, E., �lvarez, E., Dom�nguez, N., Landeira, G. & Longo, C. Natural history of nonalcoholic steatohepatitis: A longitudinal study of repeat liver biopsies. Hepatology 40, 820–826 (2004).

McPherson, S. et al. Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: implications for prognosis and clinical management. J. Hepatol. 62, 1148–55 (2015).

Singh, S. et al. Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta-analysis of paired-biopsy studies. Clin. Gastroenterol. Hepatol. 13, 643-54-9-40 (2015).

D’Amico, G. et al. Natural history and prognostic indicators of survival in cirrhosis: A systematic review of 118 studies. J. Hepatol. 44, 217–231 (2006).

Tokushige, K., Hashimoto, E. & Kodama, K. Hepatocarcinogenesis in non-alcoholic fatty liver disease in Japan. J. Gastroenterol. Hepatol. 28 Suppl 4, 88–92 (2013).

Perumpail, R. B., Wong, R. J., Ahmed, A. & Harrison, S. A. Hepatocellular Carcinoma in the Setting of Non-cirrhotic Nonalcoholic Fatty Liver Disease and the Metabolic Syndrome: US Experience. Dig. Dis. Sci. 60, 3142–3148 (2015).

Adams, L. A. & Anstee, Q. M. A fatty liver leads to a broken heart? (2016). doi:10.1016/j.jhep.2016.02.023

Vanni, E., Marengo, A., Mezzabotta, L. & Bugianesi, E. Systemic Complications of Nonalcoholic Fatty Liver Disease: When the Liver Is Not an Innocent Bystander. Semin. Liver Dis. 35, 236–249 (2015).

El-serag, H. B. et al. Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology 126, 460–468 (2004).

Neuschwander-Tetri, B. A. Lifestyle Modification as the Primary Treatment of NASH. Clin. Liver Dis. 13, 649–665 (2009).

Church, T. S. et al. Association of cardiorespiratory fitness, body mass index, and waist circumference to nonalcoholic fatty liver disease. Gastroenterology 130, 2023–30 (2006).

Vilar, L. et al. High-fat diet: A trigger of non-alcoholic steatohepatitis? Preliminary findings in obese subjects. Nutrition 24, 1097–1102 (2008).

Assy, N., Nassar, F., Nasser, G. & Grosovski, M. Olive oil consumption and non-alcoholic fatty liver disease. World J. Gastroenterol. 15, 1809–15 (2009).

Suzuki, A. et al. Effect of changes on body weight and lifestyle in nonalcoholic fatty liver disease. J. Hepatol. 43, 1060–1066 (2005).

Promrat, K. et al. Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis. Hepatology 51, 121–9 (2010).

Lassailly, G. et al. Bariatric Surgery Reduces Features of Nonalcoholic Steatohepatitis in Morbidly Obese Patients. Gastroenterology 149, 379–388 (2015).

Sullivan, S., Kirk, E. P., Mittendorfer, B., Patterson, B. W. & Klein, S. Randomized trial of exercise effect on intrahepatic triglyceride content and lipid kinetics in nonalcoholic fatty liver disease. Hepatology 55, 1738–1745 (2012).

Keating, S. E., Hackett, D. A., George, J. & Johnson, N. A. Exercise and non-alcoholic fatty liver disease: A systematic review and meta-analysis. J. Hepatol. 57, 157–166 (2012).

Oh, S. et al. Moderate to vigorous physical activity volume is an important factor for managing nonalcoholic fatty liver disease: A retrospective study. Hepatology 61, 1205–1215 (2015).

Abdelmalek, M. F. et al. Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. Hepatology 51, 1961–1971 (2010).

Anty, R. et al. Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery. J. Hepatol. 57, 1090–1096 (2012).

Blair, S. N. Physical inactivity: the biggest public health problem of the 21st century. Br. J. Sports Med. 43, 1–2 (2009).

Dumith, S. C., Hallal, P. C., Reis, R. S. & Kohl, H. W. Worldwide prevalence of physical inactivity and its association with human development index in 76 countries. Prev. Med. (Baltim). 53, 24–28 (2011).

Lewis, B. S. & Lynch, W. D. The Effect of Physician Advice on Exercise Behavior. Prev. Med. (Baltim). 22, 110–121 (1993).

Lawlor, D. A. & Hanratty, B. The effect of physical activity advice given in routine primary care consultations: a systematic review. J. Public Health Med. 23, 219–26 (2001).

van Achterberg, T. et al. How to promote healthy behaviours in patients? An overview of evidence for behaviour change techniques. Health Promot. Int. 26, 148–62 (2011).

van der Weegen, S. et al. It’s LiFe! Mobile and Web-Based Monitoring and Feedback Tool Embedded in Primary Care Increases Physical Activity: A Cluster Randomized Controlled Trial. J. Med. Internet Res. 17, e184 (2015).




DOI: http://dx.doi.org/10.5281/zenodo.248873

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